Viral targets for vaccines against COVID-19 | Nature Reviews Immunology

https://www.nature.com/articles/s41577-020-00480-0

Viral targets for vaccines against COVID-19

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18 December 2020

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Abstract

Vaccines are urgently needed to control the coronavirus disease 2019 (COVID-19) pandemic and to help the return to pre-pandemic normalcy. A great many vaccine candidates are being developed, several of which have completed late-stage clinical trials and are reporting positive results. In this Progress article, we discuss which viral elements are used in COVID-19 vaccine candidates, why they might act as good targets for the immune system and the implications for protective immunity.