No Significant Difference in Viral Load Between Vaccinated and Unvaccinated, Asymptomatic and Symptomatic Groups Infected with SARS-CoV-2 Delta Variant | medRxiv

https://www.medrxiv.org/content/10.1101/2021.09.28.21264262v1

Interim Clinical Considerations for Use of COVID-19 Vaccines Currently Approved or Authorized in the United States

CDC now recommends that people aged 65 years and older, residents in long-term care settings, and people aged 50–64 years with underlying medical conditions should receive a booster shot of Pfizer-BioNTech’s COVID-19 Vaccine at least 6 months after completing their Pfizer-BioNTech primary series. Other groups may receive a booster shot based on their individual risk and benefit. 

 https://www.cdc.gov/vaccines/covid-19/clinical-considerations/covid-19-vaccines-us.html?CDC_AA_refVal=https://www.cdc.gov/vaccines/covid-19/info-by-product/clinical-considerations.html#pregnant

Persistence and baseline determinants of seropositivity and reinfection rates in health care workers up to 12.5 months after COVID-19 - PubMed

https://pubmed.ncbi.nlm.nih.gov/34183003/

Quantifying impacts of the COVID-19 pandemic through life-expectancy losses: a population-level study of 29 countries | International Journal of Epidemiology | Oxford Academic

https://academic.oup.com/ije/advance-article/doi/10.1093/ije/dyab207/6375510

Covid-19: England sees biggest fall in life expectancy since records began in wake of pandemic | The BMJ

https://www.bmj.com/content/374/bmj.n2291?utm_source=twitter&utm_medium=social&utm_term=hootsuite&utm_content=sme&utm_campaign=usage

When taking a step back is a veritable leap forward. Reversing decades of arthroscopy for managing joint pain: five reasons that could explain declining rates of common arthroscopic surgeries | British Journal of Sports Medicine

https://bjsm.bmj.com/content/54/22/1312

Diffusion of Innovations in Service Organizations: Systematic Review and Recommendations

 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2690184/

Opinión sanitaria : Los recursos y la prevención primaria/secundaria d...

Desde medfam he leido esta magnifica discusión sobre sangra oculta en heces si/no derivacion digestivo:

la opinion en blog Borinot.

Opinión sanitaria : Los recursos y la prevención primaria/secundaria d...:  Los recursos y la prevención primaria/secundaria del cáncer de colon Un problema que se nos ha presentado recientemente a los médicos Atenc...

Una respuesta de jose Maria Tallon en MEDfam :

Lamento volver a hacer de abogado del diablo, pero cito FMC, Protocolo de patología prostática, 2017:

"El Programa de actividades preventivas y de promoción de la salud de la Sociedad Española de Medicina de Familia y Comunitaria no recomienda el PSA de cribado en personas asintomáticas.
Las recientes recomendaciones del U.S. Preventive Task Force están en sintonía con estas recomendaciones".

En cuanto al cribado de cáncer de colon, es bien sabido que la reducción de mortalidad por dicha patología puede llegar al 22% en las mejores series siempre que se haga la TSOH cada 2 años. Pero la reducción de mortalidad total, al menos en toda la bibliografía que he consultado, que no es poca, es de 0 patatero. O sea, en mi modesta y discutible opinión, es un marrón (nunca mejor dicho) que te hace perder tiempo y te da sustos, pero para nada te alarga la vida.

Por lo tanto no me parece ningún pecado no hacer estos cribados en la consulta de Atención Primaria. 

Creo que los dos autores tienen su razón y que es bueno conocerlas para tomar nuestra decisión personal.

Assisted dying: a question of when, not if | The BMJ

https://www.bmj.com/content/374/bmj.n2128

Single-dose intranasal vaccination elicits systemic and mucosal immunity against SARS-CoV-2 - ScienceDirect

Despite remarkable progress in the development and authorization of vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), there is a need to validate vaccine platforms for broader application. The current intramuscular vaccines are designed to elicit systemic immunity without conferring mucosal immunity in the nasal compartment, which is the first barrier that SARS-CoV-2 virus breaches before dissemination to the lung. We report the development of an intranasal subunit vaccine that uses lyophilized spike protein and liposomal STING agonist as an adjuvant. This vaccine induces systemic neutralizing antibodies, IgA in the lung and nasal compartments, and T-cell responses in the lung of mice. Single-cell RNA sequencing confirmed the coordinated activation of T/B-cell responses in a germinal center-like manner within the nasal-associated lymphoid tissues, confirming its role as an inductive site to enable durable immunity. The ability to elicit immunity in the respiratory tract can prevent the establishment of infection in individuals and prevent disease transmission.

 

https://www.sciencedirect.com/science/article/pii/S2589004221010051

COVID-19 vaccines: Keeping pace with SARS-CoV-2 variants: Cell

https://www.cell.com/cell/fulltext/S0092-8674(21)01057-6


Enviado desde mi iPhone

Covid vacuna inmunodepresion cd20 artritis

https://www.thelancet.com/journals/lanrhe/article/PIIS2665-9913(21)00251-4/fulltext?s=03 

Tipos visita atencion primaria covid

https://www.jmir.org/2021/9/e29622?s=03 

Caos y gestión

https://www.dendramedica.es/revista/v5n2/Reinterpretando_la_gestion_del_sistema_sanitario_desde_las_teorias_de_la_complejidad_y_el_caos.pdf


Enviado desde mi iPhone

La utilidad de los correos masivos | Saludconcosas

https://saludconcosas.es/la-utilidad-de-los-correos-masivos/


Enviado desde mi iPhone

La gestión sanitaria orientada hacia la calidad y seguridad de los pacientes 2ª Edic

https://documentacion.fundacionmapfre.org/documentacion/publico/i18n/catalogo_imagenes/grupo.cmd?path=1101694


Enviado desde mi iPhone

An update on non-thyroidal illness syndrome | SpringerLink

https://link.springer.com/article/10.1007/s40618-020-01482-4


Enviado desde mi iPhone

Association Between Physician Part-time Clinical Work and Patient Outcomes | Health Care Quality | JAMA Internal Medicine | JAMA Network

https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/2784166


Enviado desde mi iPhone

Considerations in boosting COVID-19 vaccine immune responses

 paper de Lancet

Salud, dinero y atención primaria: ¿Evitó la vacuna tanta muerte por covid19 en ancia...

Salud, dinero y atención primaria: ¿Evitó la vacuna tanta muerte por covid19 en ancia...:   Sostiene el Ministerio de Sanidad que “las vacunas evitaron 3.500 muertes en residencias solo en el primer trimestre de 2021” ( aquí ). Se...

Medico‐legal risks associated with fragmented GP care | InSight+

https://insightplus.mja.com.au/2021/31/medico‐legal-risks-associated-with-fragmented-gp-care/

Early Warning Signs of Burnout and Functional Impairment in Healthcare Workers During the COVID-19 Pandemic

https://www.jwatch.org/na54028/2021/09/09/early-warning-signs-burnout-and-functional-impairment


Enviado desde mi iPhone

Vitamin D recommendations in clinical guidelines: A systematic review, quality evaluation and analysis of potential predictors - Fraile Navarro - - International Journal of Clinical Practice - Wiley Online Library

https://onlinelibrary.wiley.com/doi/10.1111/ijcp.14805#.YTuq4hoMMhE.twitter


Enviado desde mi iPhone

Predictors of Nonseroconversion after SARS-CoV-2 Infection

 enlace a articulo

Resultados vacunacion moderna

https://papers.ssrn.com/sol3/papers.cfm?abstract_id=3916094&s=03 

Interaction Time with Electronic Health Records: A Systematic Review

https://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-0041-1733909

Longitudinal analysis of SARS-CoV-2 vaccine breakthrough infections reveal limited infectious virus shedding and restricted tissue distribution | medRxiv

https://www.medrxiv.org/content/10.1101/2021.08.30.21262701v1


Enviado desde mi iPhone

Hospitalizations Associated with COVID-19 Among Children and Adolescents — COVID-NET, 14 States, March 1, 2020–August 14, 2021 | MMWR

https://www.cdc.gov/mmwr/volumes/70/wr/mm7036e2.htm


Enviado desde mi iPhone

Estimated US Infection- and Vaccine-Induced SARS-CoV-2 Seroprevalence Based on Blood Donations, July 2020-May 2021 | Infectious Diseases | JAMA | JAMA Network

https://jamanetwork.com/journals/jama/fullarticle/2784013?guestAccessKey=0c3ae017-8762-46e6-94df-cd1e03481fc6&utm_source=silverchair&utm_medium=email&utm_campaign=article_alert-jama&utm_content=olf&utm_term=090221

Use of artificial intelligence for image analysis in breast cancer screening programmes: systematic review of test accuracy | The BMJ

https://www.bmj.com/content/374/bmj.n1872

Risk factors and disease profile of post-vaccination SARS-CoV-2 infection in UK users of the COVID Symptom Study app: a prospective, community-based, nested, case-control study - The Lancet Infectious Diseases

https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(21)00460-6/fulltext


Enviado desde mi iPhone

Continuity in general practice as a predictor of mortality, acute hospitalization, and use of out-of-hours services: registry-based observational study in Norway | British Journal of General Practice

https://bjgp.org/content/early/2021/08/26/BJGP.2021.0340


Enviado desde mi iPhone

Resurgence of SARS-CoV-2 Infection in a Highly Vaccinated Health System Workforce | NEJM

https://www.nejm.org/doi/full/10.1056/NEJMc2112981


Enviado desde mi iPhone

First findings from world’s largest study on long COVID in children | Science Media Centre

https://www.sciencemediacentre.org/first-findings-from-worlds-largest-study-on-long-covid-in-children/


Enviado desde mi iPhone

Interferon-γ Release Assay for Accurate Detection of Severe Acute Respiratory Syndrome Coronavirus 2 T-Cell Response

https://academic.oup.com/cid/advance-article/doi/10.1093/cid/ciaa1537/5920279