Targeted protein S-nitrosylation of ACE2 inhibits SARS-CoV-2 infection | Nature Chemical Biology

https://www.nature.com/articles/s41589-022-01149-6


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How Accurate Are Home Antigen Tests for Omicron?

https://www.jwatch.org/na55354/2022/09/27/how-accurate-are-home-antigen-tests-omicron


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REVISION GLIFOCINAS E INSUFICIENCIA CARDIACA.

https://cosago.nl/wp-content/uploads/2022/06/nejmra2115011-1.pdf

Fwd: broncodilatadores sin epoc??

Los broncodilatadores en pacientes fumadores sintomaticos sin criterios espirometricos de EPOC no son efectivos.

https://www.nejm.org/doi/full/10.1056/NEJMoa2204752

Improving breast cancer diagnostics with deep learning for MRI | Science Translational Medicine

https://www.science.org/doi/10.1126/scitranslmed.abo4802

Long-term neurologic outcomes of COVID-19 | Nature Medicine

https://www.nature.com/articles/s41591-022-02001-z

Infection Control: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) | CDC

https://www.cdc.gov/coronavirus/2019-ncov/hcp/infection-control-recommendations.html


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Duration of viral infectiousness and correlation with symptoms and diagnostic testing in non-hospitalized adults during acute SARS-CoV-2 infection: A longitudinal cohort study | medRxiv

https://www.medrxiv.org/content/10.1101/2022.09.26.22280387v1


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Long-term cardiac pathology in individuals with mild initial COVID-19 illness | Nature Medicine

https://www.nature.com/articles/s41591-022-02000-0

Tweet de Eric Topol en Twitter

	Eric Topol ⁦‪@EricTopol‬⁩ New ⁦‪@CellCellPress‬⁩ Why getting a booster too soon after Covid is not a good idea: suboptimal B-cell response cell.com/cell/fulltext/… ⁦‪@NIAIDNews‬⁩ pic.twitter.com/GGMfM2OATG   27/9/22, 15:33

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Finding the equilibrium of empathy | The BMJ

https://www.bmj.com/content/378/bmj.o2288


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Managing peripheral oedema caused by calcium channel blockers – SPS - Specialist Pharmacy Service – The first stop for professional medicines advice

https://www.sps.nhs.uk/articles/managing-peripheral-oedema-caused-by-calcium-channel-blockers/


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Más eficacia de inmunidad hibrida( vacuna infección)covid

https://www.cell.com/iscience/pdf/S2589-0042(22)01474-2.pdf?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS2589004222014742%3Fshowall%3Dtrue

Nanoparticle-modified microrobots for in vivo antibiotic delivery to treat acute bacterial pneumonia | Nature Materials

https://www.nature.com/articles/s41563-022-01360-9


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Genetics and mechanisms of thoracic aortic disease | Nature Reviews Cardiology

https://www.nature.com/articles/s41569-022-00763-0


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Tweet de Jose Gomez Rial en Twitter

	Jose Gomez Rial ⁦‪@gomez_rial5‬⁩ Identifican tres categorías de respondedores a la vacunación ARNm según niveles de Ac (S y RBD), células B reactivas (S) y células T polireactivas. La respuesta inmune es global (humoral y celular) *Leer con calma* Memory CD8+ T cell diversity and B cell nature.com/articles/s4159…   24/9/22, 9:45

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Guía práctica sobre el diagnóstico y tratamiento de la hipertensión arterial en España, 2022. Sociedad Española de Hipertensión - Liga Española para la Lucha contra la Hipertensión Arterial (SEH-LELHA) | Hipertensión y Riesgo Vascular

Ahora que me incorporo de nuevo a primaria esta guia es un clásico para revisar.

https://www.elsevier.es//es-revista-hipertension-riesgo-vascular-67-avance-resumen-guia-practica-sobre-el-diagnostico-S1889183722000666

Recomendaciones OMS rehabilitación long Covid

https://apps.who.int/iris/bitstream/handle/10665/362783/WHO-2019-nCoV-Clinical-2022.2-eng.pdf

La consulta del doctor Casado: Covid persistente y secuelas Covid

https://doctorcasado.blogspot.com/2022/06/covid-persistente-y-secuelas-covid.html


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Long-term neurologic outcomes of COVID-19 | Nature Medicine

https://www.nature.com/articles/s41591-022-02001-z


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Long covid—an update for primary care | The BMJ

No os perdais esta actualizacion sobre long covid desde perspectiva de atencion primaria.

https://www.bmj.com/content/378/bmj-2022-072117

The economics of medication safety : Improving medication safety through collective, real-time learning | OECD Health Working Papers | OECD iLibrary

Cite this content as:

de Bienassis, K., et al. (2022), "The economics of medication safety: Improving medication safety through collective, real-time learning", OECD Health Working Papers, No. 147, OECD Publishing, Paris,https://doi.org/10.1787/9a933261-en.

https://www.oecd-ilibrary.org/social-issues-migration-health/the-economics-of-medication-safety_9a933261-en

IL-1RA Antibodies in Myocarditis after SARS-CoV-2 Vaccination | NEJM

https://www.nejm.org/doi/full/10.1056/NEJMc2205667

Timing of Anticoagulants in Stroke Related to Atrial Fibrillation

https://www.jwatch.org/na55346/2022/09/19/timing-anticoagulants-stroke-related-atrial-fibrillation


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Nanomolar inhibition of SARS-CoV-2 infection by an unmodified peptide targeting the prehairpin intermediate of the spike protein | PNAS

https://www.pnas.org/doi/10.1073/pnas.2210990119

Estáticas en mayores de 70 años

https://sanidad.castillalamancha.es/sites/sescam.castillalamancha.es/files/documentos/farmacia/bft_2022_1_estatinas_en_mayores_de_75_anos_.pdf

Association Between BNT162b2 Vaccination and Long COVID After Infections Not Requiring Hospitalization in Health Care Workers | Vaccination | JAMA | JAMA Network

https://jamanetwork.com/journals/jama/fullarticle/2794072


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Overdiagnosis and overuse of diagnostic and screening tests in low-income and middle-income countries: a scoping review

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9442491/


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Análisis de causas de las causas de futuras pandemias: los retos para una nueva salud pública - ScienceDirect

https://www.sciencedirect.com/science/article/pii/S0213911122001315#fig0005

dispositivos y epoc

https://scientiasalut.gencat.cat/bitstream/handle/11351/8191/butll_prev_errors_medicacio_catalunya_2022_20_02_cas.pdf

Evaluation of medication dose adjustments in patients with impaired renal function using different online drug information databases | European Journal of Hospital Pharmacy

https://ejhp.bmj.com/content/29/5/255


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Los orígenes del «No hacer» fueron el profesionalismo y la ética médica | Primum non nocere 2022

https://rafabravo.blog/2018/12/08/los-origens-del-no-hacer-fueron-el-profesionalismo-y-la-etica-medica/


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Anti-Spike Mucosal IgA Protection against SARS-CoV-2 Omicron Infection | NEJM

https://www.nejm.org/doi/full/10.1056/NEJMc2209651


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The Lancet Commission on lessons for the future from the COVID-19 pandemic - The Lancet

https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(22)01585-9/fulltext


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The Lancet COVID-19 Commission

https://www.thelancet.com/commissions/covid19


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CADIME - Recomendaciones para el uso racional de anticoagulantes orales directos.

https://www.cadime.es/noticias/destacados/956-recomendaciones-para-el-uso-racional-de-anticoagulantes-orales-directos.html


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Preevid: Sulfato de glucosamina y condroitín sulfato en la artrosis. / Glucosamine sulfato and chondroitin sulfate in osteoarthritis.

Revisión de todas las evidencias.


https://www.murciasalud.es/preevid/24839#


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Australia ends daily COVID reporting after deadliest month of the pandemic - World Socialist Web Site

Cifras altas de mortalidad Covid en Australia.

https://www.wsws.org/en/articles/2022/09/10/covi-s10.html


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Are Doctors Getting Their COVID Boosters? | MedPage Today

https://www.medpagetoday.com/special-reports/exclusives/100665


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How to diagnose heart failure with preserved ejection fraction: the HFA–PEFF diagnostic algorithm: a consensus recommendation from the Heart Failure Association (HFA) of the European Society of Cardiology (ESC) | European Heart Journal | Oxford Academic

https://academic.oup.com/eurheartj/article/40/40/3297/5557740


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Is 112 the New 10 000?—Step Count and Dementia Risk in the UK Biobank | Dementia and Cognitive Impairment | JAMA Neurology | JAMA Network

https://jamanetwork.com/journals/jamaneurology/fullarticle/2795818


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Effectiveness of a Fourth Dose of COVID-19 mRNA Vaccine Against Omicron Variant Among Elderly People in Singapore | Annals of Internal Medicine

https://www.acpjournals.org/doi/10.7326/M22-2042


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SARS-CoV-2 in immunocompromised individuals: Immunity

https://www.cell.com/immunity/fulltext/S1074-7613(22)00500-3


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Understanding myalgic encephalomyelitis | Science

https://www.science.org/doi/10.1126/science.abo1261


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https://www.nature.com/articles/s41591-022-02000-0


En casos leves de Covid a los 100 días hasta 70%reportaban síntomas cardiológicos. Los siguieron con Rmn cardíaca…
https://www.nature.com/articles/s41591-022-02000-0


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Open-Source Automated Insulin Delivery in Type 1 Diabetes | NEJM

https://www.nejm.org/doi/full/10.1056/NEJMoa2203913


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Risk for Muscle Pain or Weakness with Statins Is Slight

https://www.jwatch.org/na55300/2022/09/06/risk-muscle-pain-or-weakness-with-statins-slight


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Growing Role of Gabapentin in Opioid-Related Overdoses Highlights Misuse Potential and Off-label Prescribing Practices | Clinical Pharmacy and Pharmacology | JAMA | JAMA Network

https://jamanetwork.com/journals/jama/fullarticle/2796287?guestAccessKey=b12b5e0b-0761-4db8-ba83-a78cac0c93bd&utm_source=silverchair&utm_medium=email&utm_campaign=article_alert-jama&utm_content=olf&utm_term=090722


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Durability of Booster mRNA Vaccine against SARS-CoV-2 BA.2.12.1, BA.4, and BA.5 Subvariants | NEJM

https://www.nejm.org/doi/full/10.1056/NEJMc2210546


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Podcast 298: COPD exacerbations — 7 days of antibiotics versus 2 | Clinical Conversations

https://podcasts.jwatch.org/index.php/podcast-298-copd-exacerbations-7-days-of-antibiotics-versus-2/2022/09/02/


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Pruebas de imagen osteomuscular innecesarias como mejorar??

 Entre los médicos generales australianos que solicitan con frecuencia imágenes de diagnóstico musculoesquelético, una auditoría individualizada y una intervención de retroalimentación, en comparación con ninguna intervención, disminuyó significativamente la tasa de pruebas de imágenes musculoesqueléticas dirigidas ordenadas durante 12 meses

https://jamanetwork.com/journals/jama/fullarticle/2795890?guestAccessKey=a9321398-3aa5-4f0b-a362-ef3434b9f102&utm_source=silverchair&utm_medium=email&utm_campaign=article_alert-jamainternalmedicine&utm_content=olf&utm_term=090622

Long-term cardiac pathology in individuals with mild initial COVID-19 illness | Nature Medicine

https://www.nature.com/articles/s41591-022-02000-0


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The pride of being a family physician | The College of Family Physicians of Canada

El orgullo de ser un médico de familia.
https://www.cfp.ca/content/68/8/563


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Updates on COVID-19 Vaccine Effectiveness during Omicron

Actualizacion de la CDC de la efectividad de la vacuna. 

https://www.cdc.gov/vaccines/acip/meetings/downloads/slides-2022-09-01/04-COVID-Link-Gelles-508.pdf

Evasión de anticuerpos neutralizantes por sublinaje omicron BA.2.75

 Un sublinaje emergente, BA.2.75, está aumentando en frecuencia en India y se había detectado en al menos 15 países hasta el 19 de julio de 2022. Al parecer mantiene una menor frecuencia de escape que BA.5 y es aun sensible a algunos farmacos.

https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(22)00524-2/fulltext

How covid-19 spreads: narratives, counter narratives, and social dramas

Relato de como discusión entre transmision gotas versus aire genero consecuencias desfavorables en UK: 

https://www.bmj.com/content/378/bmj-2022-069940

Frequency and estimated costs of ten low-value practices in the Spanish primary care: a retrospective study: Expert Opinion on Drug Safety: Vol 21, No 7

https://www.tandfonline.com/doi/full/10.1080/14740338.2022.2026924


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Recent SARS-CoV-2 infection abrogates antibody and B-cell responses to booster vaccination | medRxiv

Preprint donde establece que el haber pasado la infección disminuye respuesta del booster por lo que hay que separarlo unos meses.

https://www.medrxiv.org/content/10.1101/2022.08.30.22279344v1


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JMIR Research Protocols - Using Artificial Intelligence as a Diagnostic Decision Support Tool in Skin Disease: Protocol for an Observational Prospective Cohort Study

https://www.researchprotocols.org/2022/8/e37531


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Risk of BA.5 Infection among Persons Exposed to Previous SARS-CoV-2 Variants | NEJM

En este articulo refuta el argumento de que infecciones previas de omicron no protegen de nuevas variantes de la misma.

We found that previous SARS-CoV-2 infection had a protective effect against BA.5 infection (Figure 1B and Table S1 in the Supplementary Appendix, available with the full text of this letter at NEJM.org), and this protection was maximal for previous infection with BA.1 or BA.2

https://www.nejm.org/doi/full/10.1056/NEJMc2209479


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